A phentermine weight loss drug acts as an appetite suppressant that has been approved to aid obese patients in weight loss. The phentermine weight loss drug is meant for short-term usage while combined with proper diet, regular exercise, and a change in lifestyle. It is also prescribed to those who are at risk for certain medical and health risks related to their weight since it works by releasing chemicals in the brain to control the appetite.
History of phentermine
The generic phentermine weight loss drug received FDA-approval in 1959 as an appetite suppressant. However, since its release, no medical studies have been performed on the drug, although the most recent study done in 1990 combined fenfluramine (dexfenfluramine) with it and it was called Fen-Phen. The new variety never received any approval from the FDA but a 1992 study stated that it is more effective compared to exercising and dieting. Furthermore, it had fewer side effects. Unfortunately, by 1997, there were 24 reported cases of heart valve diseases regarding people who have taken Fen-Phen, which led to the FDA taking action by removing the drug from the market.
Names for phentermine
In the 70's, it was sold by King Pharmaceuticals as Fastin for SmithKline Beecham; but in 1998, the product was taken out from the market. Phentermine is also being sold by Medeva Pharmaceuticals with the name Ionamin, while Gate Pharmaceuticals is selling it as Adipex-P. Other commercial brand names for the phentermine weight loss drug are the following:
8. Pro-Fast SA
14. Phentermine Trenker
Several varieties of the phentermine weight loss drug are still available in a lot of countries, especially in the United States. However, it is possible that the user can develop an addiction to the drug since it is similar to amphetamines. That is why it is also classified as a controlled substance in a lot of countries.
How it works
The phentermine weight loss drug works with the brain by stimulating and releasing the right amount of particular neurotransmitters responsible for appetite control. By releasing those neurotransmitters, the body is able to think that it is not hungry since the brain is not able to receive hunger messages.
Since it contributes to the risk of insomnia, it is recommended that you take the drug before breakfast or around 1 to 2 hours after eating it. The FDA recommends that a phentermine weight loss drug should be for short-term usage only, which can last up to 12 weeks and paired with other means for weight loss such as regular exercise and a healthy and balanced diet.
Why dosage is limited
Dosage is being limited because the possible onset of drug tolerance wherein phentermine can lose its effects once the body learns how to adjust to it. However, there are contradicting reports like the drug still working even during trial for that lasted up to 36 weeks.
The following should not take any kind of phentermine weight loss drug:
o Patients who are allergic to any of the ingredients
o Those who have high blood pressure, glaucoma, cardiovascular disease, an overactive thyroid, or those with narrow blood vessels
o Patients who are experiencing anxiety attacks or diagnosed with anxiety disorders
o Those with a history or experience with substance abuse
o Pregnant, breast feeding, and women who have plans on becoming pregnant
o Those taking nonprescription or prescription medicines, dietary supplements, and herbal medications
o Those who are allergic to foods, medicines and other substances
o Patients with spinal cord or brain disorders, diabetes, and high cholesterol levels
Medicines that interfere with phentermine
There are medicines that can affect the user when used with phentermine. Examples are dedfenfluramine, fenfluramine, MAOIs, or furazolidone. They increase the risk for side effects like severe headaches, slower heart rates, elevated temperature, lung problems, and high blood pressure. The risk of side effects of medicines with serotonin inhibitors can also increase with the use of phentermine. On the other hand, the effectivness of guanethidine or guanadrel can be lessened when used with phentermine.
Common side effects
While phentermine can be well tolerated by a user, it also has possible side effects that can affect different aspects of the user's health. Common side effects are insomnia, high blood pressure, irritability, anxiety and nervousness, blurred vision, a change in sexual desire, confusion, diarrhea, dry mouth, psychosis, tiredness, unpleasant taste, nausea, headaches, seizures, dizziness, panic attacks, hallucinations, restlessness, weakness, stomach cramps, depression, etc.